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. 2017 Mar 3;7:52. doi: 10.1038/s41598-017-00104-z

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© The Author(s) 2017

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Inhibition of lesion development in the aortic root by 15a. (a) Also in the aortic root, 15a inhibited atherosclerotic lesion development after 6 weeks of Western type diet. (b) Lesion area in the aortic roots presented for each group every 90 μm of the aortic root. (c) Plaque volume was also significantly reduced in the 15a-treated group. *P < 0.05, **P < 0.01. Graphs shown are representative from one experiment with n = 10 controls versus n = 9 15a-treated mice.