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. 2017 Mar 8;7:118. doi: 10.1038/s41598-017-00118-7

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© The Author(s) 2017

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Asrij expression is modulated upon infection and in immune mutants. (A,B) qRT-PCR analysis of adult flies showing that asrij mRNA levels are down-regulated 24 and 48 hours post infection (A) and that asrij transcript levels vary among immune mutants (B). (C) Model illustrating loss of immune homeostasis in ARF1-Asrij depleted conditions leading to compromised survival of the flies.