Table 1.

Tissue uptake parameters found in literature for various cell types and the typical value used in the models.

Tissue uptake parameters		Minimum	Maximum	Typical
Tissue cellular density ρ cell (cell/μL)		2.1 × 105  47	4.0 × 105  48	2.8 × 105
Maximum cellular uptake rate q max (mol/cells · s)	Glucose	2.7 × 10−18  49	2.5 × 10−16  50	3.9 × 10−17
	Oxygen	1.7 × 10−18  51	7.0 × 10−16  52	7.4 × 10−17
Michaelis-Menten constant k M (mM)	Glucose	4 × 10−2  47	6 × 10−2  49	4 × 10−2
	Oxygen	4.6 × 10−3  50	6.9 × 10−3  53	4.63 × 10−3
Diffusion constant of O2 D x (cm2/s)	Medium	2 × 10−5  46	3.35 × 10−5  52	2.44 × 10−5
	Tissue	9.5 × 10−6  29	3.6 × 10−5  54	1.85 × 10−5
Saturation concentration of O2 c x-sat (mM)	Medium	—	—	0.2110
	Tissue	—	—	1.0229, 55