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. 2017 Mar 8;8(5):3726–3740. doi: 10.1039/c6sc04094b

Table 1. Effect of cleavage activity with and without inhibitors at varying concentrations in the cleavage activity of 44+ and 32+ with GSH and plasmid DNA under aerobic conditions after 24 h incubation.

Inhibitor
% Form II cleavage from 44+ digestion % Form II cleavage from 32+ digestion
Benzoate (mM) 0 74 74
2 44 53
4 33 40
6 30 36
Formate (mM) 0 62 75
2 44 57
4 30 43
6 27 39
Mannitol (mM) 0 67 71
2 55 53
4 39 49
6 39 36
EtOH (mM) 0 71 79
2 54 55
4 39 46
6 39 45
Pyruvate (mM) 0 74 78
2 30 34
4 31 28
6 28 23
DMSO (mM) 0 64 74
2 43 50
4 34 37
6 31 31
DEF (mM) 0 65 50
2 26 19
4 22 17
6 22 17
SOD (μg mL–1) 0 64 77
15 39 50
Catalase (μg mL–1) 0 67 75
15 19 18
SOD and catalase (μg mL–1) 0 67 75
15 20 20