Table 2.
Functional description of candidate genes responsible for BBP regulation of EN-MSCs.
| Skeletal and Muscular Disorders | Cell Morphology | Tissue Development | |||
|---|---|---|---|---|---|
| Symbol | Gene description | Symbol | Gene description | Symbol | Gene description |
| ALX1 | ALX homeobox 1 | ASIC2 | acid-sensing (proton-gated) ion channel 2 | ADAM28 | ADAM metallopeptidase domain 28 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | BCMO1 | beta-carotene 15,15′-monooxygenase 1 | ALX1 | ALX homeobox 1 |
| CASP192 | caspase 192 | CASP1 | caspase 1, apoptosis-related cysteine peptidase | CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CCL23 | chemokine (C-C motif) ligand 23 | CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | CDH24 | cadherin 24, type 2 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | ESRRG | estrogen-related receptor gamma | GLIS3 | GLIS family zinc finger 3 |
| CHEK2 | checkpoint kinase 2 | GHRL | ghrelin/obestatin prepropeptide | HIPK1 | homeodomain interacting protein kinase 1 |
| CHRM2 | cholinergic receptor, muscarinic 2 | GLIS3 | GLIS family zinc finger 3 | HYAL1 | hyaluronoglucosaminidase 1 |
| COL9A3 | collagen, type IX, alpha 3 | IGLL1 | immunoglobulin lambda-like polypeptide 1 | LHX9 | LIM homeobox 9 |
| FASLG | Fas ligand (TNF superfamily, member 6) | KIF18B | kinesin family member 18 | OTX1 | orthodenticle homeobox 1 |
| GYPA | glycophorin A (MNS blood group) | MTMR3 | myotubularin related protein 3 | OVOL1 | ovo-like 1 (Drosophila) |
| HIPK | homeodomain interacting protein kinase 1 | NOBOX | NOBOX oogenesis homeobox | PITX2 | paired-like homeodomain 2 |
| HYAL1 | hyaluronoglucosaminidase 1 | PITX2 | paired-like homeodomain 2 | PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| KCNE3 | potassium voltage-gated channel, Isk-related family, member 3 | PTGER3 | prostaglandin E receptor 3 (subtype EP3) | PTPRC | protein tyrosine phosphatase, receptor type, C |
| KCNJ15 | potassium inwardly-rectifying channel, subfamily J, member 15 | PTPRC | protein tyrosine phosphatase, receptor type, C | RGS3 | regulator of G-protein signaling 3 |
| MDM2 | Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) | RGS3 | regulator of G-protein signaling 3 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | TCF12 | transcription factor 12 |
| OTX1 | orthodenticle homeobox 1 | TLR2 | toll-like receptor 2 | TDGF1 | teratocarcinoma-derived growth factor 1 |
| PHACTR3 | phosphatase and actin regulator 3 | ZP3 | zona pellucida glycoprotein 3 (sperm receptor) | TLR2 | toll-like receptor 2 |
| PITX2 | paired-like homeodomain 2 | WWOX | WW domain containing oxidoreductase | ||
| PTPRC | protein tyrosine phosphatase, receptor type, C | ZP3 | zona pellucida glycoprotein 3 (sperm receptor) | ||
| SLC22 A12 | solute carrier family 22 (organic anion/urate transporter), member 12 | ||||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | ||||
| TLR2 | toll-like receptor 2 | ||||
| TPIM10 | ? | ||||
| WWOX | WW domain containing oxidoreductase | ||||
| ZNF | zinc finger protein | ||||