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. 2017 Mar 15;7:199. doi: 10.1038/s41598-017-00241-5

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© The Author(s) 2017

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Comparison of retinal gliosis after single and combined cell transplantation into subretinal space (SRS). (a–t) Representative image of GFAP-staining Müller cells in untreated group and within grafted area after PBS, human retinal progenitor cells (HRPCs), human bone mesenchymal stem cells (HBMSCs) and combined cells injection on corresponding 3, 6, 9 and 12 post operational weeks. (u) Statistical analysis of the area of total GFAP positive cells the in all 5 groups at 4 time points. (v) Statistical analysis of the light density of GFAP positive cells the in all 5 groups at 4 time points. *P < 0.05; **P < 0.01; ***P < 0.001. (n = 3).