Table 5.
Antimicrobial activity of degradation products of ciprofloxacin against Escherichia coli, Staphylococcus aureus and Streptococcus pyogenes
| Concentration of CIP used ( in ppm) | Zone of inhibition (in cm)a | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| E. coli | S. aureus | S. pyogenes | |||||||
| CIP degradation products | CIP | CD 5% | CIP degradation products | CIP | CD 5% | CIP degradation products | CIP | CD 5% | |
| D/w | ND | ND | – | ND | ND | – | ND | ND | – |
| 0(Control) | 1.5 | 3.0 | 0.226 | 1.6 | 3.8 | 0.358 | 2.0 | 3.6 | 0.358 |
| 100 | 1.9 | 2.5 | 0.226 | 1.7 | 2.0 | 0.226 | 2.3 | 2.8 | 0.240 |
| 200 | 1.9 | 3.0 | 0.226 | 2.5 | 2.8 | 0.226 | 2.5 | 3.0 | 0.226 |
| 300 | 2.3 | 3.4 | 0.358 | 2.5 | 3.0 | 0.321 | 2.5 | 3.2 | 0.330 |
| 400 | 2.6 | 3.6 | 0.321 | 2.6 | 3.4 | 0.330 | 2.1 | 3.2 | 0.160 |
| 500 | 2.9 | 4.0 | 0.179 | 2.6 | 3.6 | 0.330 | 2.6 | 3.4 | 0.320 |
Medium used—Mueller Hinton Agar; Temperature conditions 37 ± 2 °C
D/w distilled water, CIP ciprofloxacin, ND not detected
aAverage of triplicates