Table 1.
Scoring systems for primary myelofibrosis.
| Variables | IPSS20 | DIPSS22 | DIPSS-plus23 |
|---|---|---|---|
| Age >65 y | 1 | 1 | 1 |
| Constitutional symptoms | 1 | 1 | 1 |
| Hb <10 g/dL | 1 | 2 | 1 |
| WBC count >25 × 109/L | 1 | 1 | 1 |
| Peripheral blood blasts ⩾1% | 1 | 1 | 1 |
| PLT count <100 × 109/L | — | — | 1 |
| RBC transfusion need | — | — | 1 |
| Unfavourable karyotype (+8, −7/7q−, i(17q), −5/5q−, 12p−, inv(3), 11q23) |
— | — | 1 |
Abbreviations: DIPSS, Dynamic International Prognostic Scoring System; Hb, haemoglobin; IPSS, International Prognostic Scoring System; PLT, platelets; RBC, red blood cell; WBC, white blood cell.
IPSS: 0, low risk; 1, intermediate-1 risk; 2, intermediate-2 risk; ⩾3, high risk. DIPSS: 0, low risk; 1 or 2, intermediate-1 risk; 3 or 4, intermediate-2 risk; more than 4, high risk. DIPSS-plus: 0, low risk; 1, intermediate-1 risk; 2 or 3, intermediate-2 risk; ⩾4, high risk.