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Effects of siRNA of AdipoR1 and AMPK inhibitor compound C on APN-reduced expression of iNOS and nitrotyrosine and production of NO and ONOO−. A, Expression of iNOS and nitrotyrosine. Expression of β-actin was a loading control. B, Production of NO. C, Production of ONOO−. **, P < 0.01 vs. control group (con); ##, P < 0.01 vs. LPS; $$, P < 0.01 vs. APN + LPS. Values are means ± sem.
