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. 2017 Mar 22;7:291. doi: 10.1038/s41598-017-00397-0

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© The Author(s) 2017

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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JB253 and insulin secretion. (a) Box and whiskers plot showing that insulin secretion, normalized as the ratio insulin:glucose, tends to increase during illumination in JB253-treated animals (median and range shown). (b) As for (a), but scatter plot to show the presence of a single outlier (mean is shown). (c) Before-and-after plot showing that glucose concentrations decreased during illumination in all JB253-treated animals examined. **P < 0.01, paired Student’s t-test.