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Resveratrol-induced cellular senescence can be attenuated by NAC. (A) U2OS cells were treated with different concentration of RSV for 48 h. ROS was measured by flow cytometry. Data summary was shown on the right, Mean of three independent experiments with SEM is shown. *P < 0.05, **P < 0.01. (B) NAC attenuates RSV induced senescence. U2OS cells were incubated with RSV with or without addition of the NAC, on day 7, cells were examined for SA-β-gal activity.
