Table 2.

GMV, CBF and CBF/GMV ratio changes in schizophrenia patients.

Brain regions*	MNI coordinates (x, y, z)	Peak t value	Cluster size (Voxels)**
GMV and CBF reduction
Anterior cingulate cortex	2, 36, 24	−7.23	699
Left anterior insular cortex	−34, 22, 2	−6.38	248
GMV reduction and normal CBF
Right insular cortex	33, 22, −4	−7.56	1596
Left medial prefrontal cortex	−8, 50, 14	−7.12	1118
Left amygdala	−20, 2, −18	−6.99	420
Left superior temporal gyrus	−52, 0, −2	−6.83	508
Right posterior mid-cingulate cortex	8, 18, 36	−6.57	212
Left posterior mid-cingulate cortex	−8, 22, 34	−6.20	138
Left middle temporal gyrus	−60, −36, 2	−6.02	188
Thalamus	0, −6, 4	−5.57	203
Reduced CBF and normal GMV
Right anterior cingulate cortex	4, 36, 24	−7.14	768
Left lateral prefrontal cortex	−30, 60, 2	−6.62	418
Increased CBF and normal GMV
Left putamen	−30, −10, −2	6.38	125
Right putamen	32, −2, 2	6.05	236

*Multiple comparisons are corrected using a family-wise error method (p < 0.05, cluster size >100 voxels).

**Voxel size is 2 × 2 × 2 mm³.