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. 2017 Mar 23;7:349. doi: 10.1038/s41598-017-00375-6

Table 2.

Semi-quantitative distribution of CDV antigen in various non-central nervous system tissues by immunohistochemistry.

Case Lymphoid organsa Respiratoryb Stomach Intestinec Kidneyd UB Otherse
LN SP TS BE PAM
No. 1 NS ++ NS + ++ NS + +/RP NS
No. 2 NS ++ NS + ++ +++ +++ +/RP ++ +/KC
No. 3 NS ++ NS + ++ NS NS ++/RP NS
No. 4 ++ ++ NS ++ ++ NS +++/PP +/RP NS
No. 5 +++ ++ ++ + ++ NS ++ ++/RP ++
No. 6 ++ +++ ++ +++ ++ +++ +++ ++/RP NS +/KC
No. 7 ++ ++ NS ++ + NS +/RP +
No. 8 NS +++ NS + ++ ++ ++ ++/RP ++ +/KC
No. 9 ++ + NS +++ ++ ++ +/RP +
No. 10 NS
No. 11 NS +++ +++ + ++ ++ ++ +/RP ++
No. 12 ++ +++ NS + + NS NS +/RP NS ++/SK
No. 13 NS + NS + ++ NS +/KC

Immunoreactivity grading: +++ marked positive, ++ moderate positive, + slight positive, −negative. NS: no sample available. aLymphoid organs: LN: Lymph node, SP: Spleen, TS: Tonsil. bRespiratory: BE: Bronchial epithelium, PAM: Pulmonary alveolar macrophage. cIntestine: PP: Payer’s patch. dKidney: RP: Renal pelvis epithelium. eOthers: KC: Kupffer cells, SK: Skin epithelium.