Table 2.
Group difference in the minimum/maximum DTI-derived measures based on analysis of the Poisson model and TBSS.
Area | FA (Mean ± SD) | MD (×10−3 mm2/s) (Mean ± SD) | Da (×10−3 mm2/s) (Mean ± SD) | Dr (×10−3 mm2/s) (Mean ± SD) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Control | HD | p | Control | HD | p | Control | HD | p | Control | HD | p | |
mPMC | 0.42 ± 0.03 | 0.36 ± 0.04 | 0.04* | 0.62 ± 0.08 | 0.68 ± 0.04 | 0.28 | 0.94 ± 0.04 | 0.94 ± 0.05 | 0.99 | 0.54 ± 0.08 | 0.56 ± 0.02 | 0.79 |
VIP | 0.46 ± 0.01 | 0.41 ± 0.02 | 0.008* | 0.64 ± 0.02 | 0.66 ± 0.01 | 0.17 | 0.87 ± 0.04 | 0.90 ± 0.04 | 0.34 | 0.48 ± 0.05 | 0.52 ± 0.02 | 0.22 |
TAa | 0.31 ± 0.02 | 0.22 ± 0.02 | 0.002* | 0.65 ± 0.06 | 0.70 ± 0.02 | 0.25 | 0.84 ± 0.06 | 0.88 ± 0.04 | 0.36 | 0.55 ± 0.07 | 0.64 ± 0.02 | 0.09 |
MLF | 0.46 ± 0.01 | 0.39 ± 0.02 | 0.002* | 0.64 ± 0.03 | 0.66 ± 0.01 | 0.21 | 0.98 ± 0.07 | 0.99 ± 0.01 | 0.79 | 0.43 ± 0.01 | 0.51 ± 0.05 | 0.01 |
IC | 0.41 ± 0.01 | 0.36 ± 0.01 | 0.001* | 0.69 ± 0.02 | 0.74 ± 0.04 | 0.08 | 0.95 ± 0.05 | 1.01 ± 0.01 | 0.09 | 0.56 ± 0.02 | 0.60 ± 0.03 | 0.07 |
AF | 0.42 ± 0.03 | 0.36 ± 0.02 | 0.02* | 0.64 ± 0.03 | 0.69 ± 0.05 | 0.15 | 0.89 ± 0.06 | 0.99 ± 0.06 | 0.07 | 0.47 ± 0.06 | 0.54 ± 0.03 | 0.11 |
CC | 0.67 ± 0.04 | 0.58 ± 0.01 | 0.02* | 0.68 ± 0.02 | 0.77 ± 0.01 | 0.001* | 1.11 ± 0.09 | 1.06 ± 0.04 | 0.43 | 0.44 ± 0.01 | 0.49 ± 0.02 | 0.01 |
StB | 0.41 ± 0.02 | 0.35 ± 0.02 | 0.01* | 0.68 ± 0.04 | 0.80 ± 0.04 | 0.008 | 1.10 ± 0.14 | 1.13 ± 0.05 | 0.68 | 0.47 ± 0.03 | 0.62 ± 0.04 | 0.002* |
UF | 0.35 ± 0.02 | 0.29 ± 0.02 | 0.007* | 0.62 ± 0.06 | 0.72 ± 0.09 | 0.14 | 0.94 ± 0.03 | 0.92 ± 0.20 | 0.87 | 0.51 ± 0.06 | 0.58 ± 0.06 | 0.20 |
MdLF | 0.39 ± 0.01 | 0.33 ± 0.02 | 0.004* | 0.61 ± 0.06 | 0.69 ± 0.04 | 0.10 | 0.93 ± 0.06 | 0.96 ± 0.04 | 0.56 | 0.50 ± 0.06 | 0.58 ± 0.03 | 0.08 |
CB | 0.44 ± 0.02 | 0.38 ± 0.01 | 0.01* | 0.67 ± 0.08 | 0.71 ± 0.07 | 0.42 | 0.94 ± 0.10 | 1.04 ± 0.08 | 0.22 | 0.50 ± 0.02 | 0.55 ± 0.05 | 0.16 |
SS | 0.32 ± 0.02 | 0.26 ± 0.02 | 0.01* | 0.70 ± 0.05 | 0.72 ± 0.02 | 0.73 | 0.90 ± 0.07 | 0.98 ± 0.04 | 0.17 | 0.60 ± 0.05 | 0.59 ± 0.02 | 0.64 |
dOB | 0.40 ± 0.02 | 0.36 ± 0.01 | 0.02* | 0.59 ± 0.06 | 0.68 ± 0.01 | 0.06 | 0.89 ± 0.05 | 0.95 ± 0.02 | 0.11 | 0.46 ± 0.04 | 0.55 ± 0.01 | 0.02 |
EmC | 0.47 ± 0.03 | 0.37 ± 0.04 | 0.02* | 0.65 ± 0.05 | 0.72 ± 0.04 | 0.11 | 0.94 ± 0.05 | 1.00 ± 0.05 | 0.24 | 0.49 ± 0.06 | 0.58 ± 0.06 | 0.09 |
EC | 0.36 ± 0.02 | 0.30 ± 0.01 | 0.007* | 0.63 ± 0.01 | 0.70 ± 0.02 | 0.001* | 0.94 ± 0.07 | 0.99 ± 0.02 | 0.27 | 0.56 ± 0.06 | 0.63 ± 0.03 | 0.13 |
FX | 0.36 ± 0.01 | 0.26 ± 0.02 | 0.001* | 0.79 ± 0.06 | 0.85 ± 0.08 | 0.29 | 0.99 ± 0.07 | 1.06 ± 0.02 | 0.15 | 0.64 ± 0.04 | 0.72 ± 0.05 | 0.09 |
ILF | 0.41 ± 0.02 | 0.35 ± 0.02 | 0.02* | 0.65 ± 0.05 | 0.70 ± 0.02 | 0.19 | 0.98 ± 0.04 | 1.04 ± 0.03 | 0.07 | 0.54 ± 0.04 | 0.62 ± 0.02 | 0.02 |
SLF Im | 0.42 ± 0.01 | 0.36 ± 0.03 | 0.03* | 0.63 ± 0.07 | 0.70 ± 0.04 | 0.17 | 0.94 ± 0.04 | 0.97 ± 0.04 | 0.44 | 0.50 ± 0.06 | 0.54 ± 0.02 | 0.38 |
SLF Ip | 0.37 ± 0.01 | 0.32 ± 0.02 | 0.02* | 0.65 ± 0.08 | 0.69 ± 0.02 | 0.39 | 0.88 ± 0.05 | 0.95 ± 0.07 | 0.17 | 0.52 ± 0.04 | 0.58 ± 0.06 | 0.16 |
SLF IIa | 0.56 ± 0.01 | 0.46 ± 0.01 | <0.001* | 0.63 ± 0.07 | 0.68 ± 0.03 | 0.28 | 1.03 ± 0.07 | 1.09 ± 0.06 | 0.34 | 0.42 ± 0.02 | 0.46 ± 0.03 | 0.13 |
SLF IIm | 0.55 ± 0.01 | 0.51 ± 0.01 | 0.001* | 0.58 ± 0.06 | 0.63 ± 0.02 | 0.31 | 0.90 ± 0.15 | 1.10 ± 0.06 | 0.11 | 0.41 ± 0.02 | 0.45 ± 0.02 | 0.07 |
SLF IIp | 0.36 ± 0.02 | 0.31 ± 0.02 | 0.01* | 0.58 ± 0.07 | 0.64 ± 0.04 | 0.28 | 0.78 ± 0.01 | 0.79 ± 0.02 | 0.70 | 0.51 ± 0.05 | 0.54 ± 0.06 | 0.54 |
SLF III | 0.48 ± 0.01 | 0.41 ± 0.02 | 0.002* | 0.68 ± 0.03 | 0.70 ± 0.02 | 0.30 | 0.93 ± 0.11 | 1.04 ± 0.01 | 0.18 | 0.51 ± 0.02 | 0.53 ± 0.01 | 0.11 |
These data were tested as significant group difference with independent t-test using FDR correction with q value 0.05 (*). SD: standard derivation. FA: fractional anisotropy; MD: mean diffusivity; Da: axial diffusivity; Dr: Radial diffusivity.