Table 3.
FA group difference at ages from 6 to 24 months.
Area | FA at 6 months (Mean ± SD) | FA at 12 months (Mean ± SD) | FA at 18 months (Mean ± SD) | FA at 24 months (Mean ± SD) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Control | HD | p | Control | HD | p | Control | HD | p | Control | HD | p | |
mPMC | 0.34 ± 0.02 | 0.31 ± 0.01 | 0.09 | 0.36 ± 0.02 | 0.34 ± 0.04 | 0.13 | 0.38 ± 0.01 | 0.34 ± 0.01 | 0.03* | 0.40 ± 0.02 | 0.35 ± 0.02 | 0.01* |
VIP | 0.35 ± 0.04 | 0.34 ± 0.02 | 0.66 | 0.40 ± 0.01 | 0.40 ± 0.01 | 0.60 | 0.42 ± 0.01 | 0.42 ± 0.01 | 0.86 | 0.42 ± 0.03 | 0.40 ± 0.02 | 0.45 |
TAa | 0.23 ± 0.02 | 0.20 ± 0.02 | 0.14 | 0.25 ± 0.03 | 0.22 ± 0.03 | 0.21 | 0.28 ± 0.04 | 0.22 ± 0.03 | 0.14 | 0.30 ± 0.04 | 0.22 ± 0.04 | 0.04* |
MLF | 0.37 ± 0.01 | 0.35 ± 0.02 | 0.47 | 0.38 ± 0.02 | 0.38 ± 0.01 | 0.75 | 0.41 ± 0.01 | 0.41 ± 0.02 | 0.68 | 0.42 ± 0.01 | 0.38 ± 0.02 | 0.03* |
IC | 0.32 ± 0.01 | 0.31 ± 0.01 | 0.23 | 0.37 ± 0.01 | 0.34 ± 0.01 | 0.08 | 0.39 ± 0.01 | 0.36 ± 0.01 | 0.02* | 0.41 ± 0.01 | 0.36 ± 0.01 | 0.01* |
AF | 0.27 ± 0.03 | 0.28 ± 0.05 | 0.85 | 0.30 ± 0.04 | 0.32 ± 0.03 | 0.83 | 0.35 ± 0.05 | 0.33 ± 0.05 | 0.71 | 0.38 ± 0.04 | 0.36 ± 0.07 | 0.15 |
CC | 0.53 ± 0.02 | 0.50 ± 0.03 | 0.38 | 0.56 ± 0.04 | 0.53 ± 0.02 | 0.62 | 0.59 ± 0.04 | 0.56 ± 0.01 | 0.41 | 0.62 ± 0.05 | 0.56 ± 0.02 | 0.18 |
StB | 0.33 ± 0.02 | 0.31 ± 0.03 | 0.54 | 0.36 ± 0.02 | 0.34 ± 0.02 | 0.71 | 0.38 ± 0.01 | 0.36 ± 0.03 | 0.41 | 0.39 ± 0.01 | 0.35 ± 0.02 | 0.05 |
UF | 0.24 ± 0.01 | 0.23 ± 0.04 | 0.39 | 0.26 ± 0.01 | 0.26 ± 0.01 | 0.92 | 0.29 ± 0.01 | 0.28 ± 0.04 | 0.55 | 0.32 ± 0.01 | 0.29 ± 0.02 | 0.01* |
MdLF | 0.28 ± 0.02 | 0.28 ± 0.03 | 0.88 | 0.31 ± 0.02 | 0.31 ± 0.02 | 0.93 | 0.35 ± 0.02 | 0.34 ± 0.05 | 0.77 | 0.35 ± 0.02 | 0.33 ± 0.04 | 0.28 |
CB | 0.31 ± 0.04 | 0.31 ± 0.01 | 0.87 | 0.36 ± 0.03 | 0.35 ± 0.01 | 0.49 | 0.39 ± 0.03 | 0.38 ± 0.02 | 0.56 | 0.40 ± 0.03 | 0.38 ± 0.01 | 0.33 |
SS | 0.25 ± 0.01 | 0.25 ± 0.02 | 0.28 | 0.27 ± 0.01 | 0.26 ± 0.03 | 0.40 | 0.29 ± 0.02 | 0.27 ± 0.03 | 0.34 | 0.30 ± 0.01 | 0.27 ± 0.03 | 0.05 |
dOB | 0.32 ± 0.03 | 0.32 ± 0.01 | 0.92 | 0.35 ± 0.01 | 0.35 ± 0.02 | 0.49 | 0.37 ± 0.02 | 0.36 ± 0.01 | 0.25 | 0.38 ± 0.01 | 0.36 ± 0.01 | 0.12 |
EmC | 0.28 ± 0.03 | 0.26 ± 0.02 | 0.22 | 0.32 ± 0.03 | 0.29 ± 0.01 | 0.34 | 0.35 ± 0.03 | 0.34 ± 0.01 | 0.79 | 0.39 ± 0.03 | 0.35 ± 0.01 | 0.14 |
EC | 0.23 ± 0.02 | 0.23 ± 0.01 | 0.90 | 0.27 ± 0.03 | 0.26 ± 0.01 | 0.60 | 0.31 ± 0.02 | 0.29 ± 0.02 | 0.29 | 0.34 ± 0.03 | 0.29 ± 0.02 | 0.17 |
FX | 0.24 ± 0.03 | 0.20 ± 0.02 | 0.21 | 0.27 ± 0.03 | 0.23 ± 0.02 | 0.45 | 0.29 ± 0.03 | 0.26 ± 0.02 | 0.15 | 0.33 ± 0.02 | 0.26 ± 0.02 | 0.04* |
ILF | 0.32 ± 0.03 | 0.29 ± 0.04 | 0.64 | 0.34 ± 0.03 | 0.33 ± 0.03 | 0.97 | 0.38 ± 0.02 | 0.35 ± 0.01 | 0.16 | 0.39 ± 0.03 | 0.35 ± 0.04 | 0.24 |
SLF Im | 0.30 ± 0.02 | 0.31 ± 0.02 | 0.80 | 0.36 ± 0.02 | 0.33 ± 0.02 | 0.16 | 0.38 ± 0.03 | 0.35 ± 0.01 | 0.26 | 0.39 ± 0.01 | 0.35 ± 0.02 | 0.007* |
SLF Ip | 0.26 ± 0.04 | 0.23 ± 0.01 | 0.39 | 0.29 ± 0.04 | 0.25 ± 0.02 | 0.19 | 0.32 ± 0.03 | 0.27 ± 0.03 | 0.18 | 0.35 ± 0.04 | 0.31 ± 0.03 | 0.18 |
SLF IIa | 0.42 ± 0.03 | 0.41 ± 0.02 | 0.50 | 0.46 ± 0.03 | 0.44 ± 0.02 | 0.35 | 0.49 ± 0.03 | 0.47 ± 0.01 | 0.42 | 0.53 ± 0.01 | 0.47 ± 0.02 | 0.03* |
SLF IIm | 0.44 ± 0.02 | 0.42 ± 0.04 | 0.55 | 0.47 ± 0.03 | 0.46 ± 0.05 | 0.81 | 0.50 ± 0.03 | 0.50 ± 0.03 | 0.83 | 0.52 ± 0.03 | 0.50 ± 0.04 | 0.66 |
SLF IIp | 0.22 ± 0.02 | 0.21 ± 0.02 | 0.16 | 0.27 ± 0.04 | 0.25 ± 0.02 | 0.36 | 0.30 ± 0.02 | 0.27 ± 0.03 | 0.10 | 0.33 ± 0.04 | 0.29 ± 0.03 | 0.98 |
SLF III | 0.33 ± 0.01 | 0.33 ± 0.03 | 0.08 | 0.38 ± 0.01 | 0.39 ± 0.02 | 0.90 | 0.41 ± 0.01 | 0.42 ± 0.01 | 0.31 | 0.45 ± 0.01 | 0.40 ± 0.03 | 0.002* |
The data were tested with a two-way ANOVA and post-hoc analysis with significant level of p < 0.05 (*). SD: standard derivation. FA: fractional anisotropy.