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. 2017 Mar 22;7:230. doi: 10.1038/s41598-017-00377-4

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© The Author(s) 2017

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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S. japonicum infection promotes the expression of fibrotic factors in hepatocytes. (A and B) Real-time PCR and western blotting were used to examine the expression of CTGF and TGF-β in primary hepatocytes purified from schistosomiasis-infected livers 6 and 12 weeks after infection. (C) Liver sections were immunohistochemically stained for CTGF and TGF-β. Sj, S. japonicum. Scale bar, 100 μm (left) and 25 μm (right). Data represent the mean ± SEM; n = 5 (*P < 0.05).