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. 2017 Feb 8;7:14. doi: 10.1038/s41598-017-00045-7

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© The Author(s) 2017

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The KCNB1 overexpression induces autophagy via ERK pathway. (A) The expression level of phospho-ERK1/2, ERK1/2, phospho-JNK1/2, JNK1/2, phospho-p38, and p38 were detected by western blot analysis in U87MG and U118MG cells (KCNB1+ vs CTR). (B) Western blot analyses of phospho-ERK1/2 and LC3-II were performed in KCNB1+ cells treated by U0126 or si-ERK.