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. 2017 Mar 6;7:72. doi: 10.1038/s41598-017-00067-1

Figure 3.

Figure 3

Rv2170 encodes GNAT acetyltransferase. (A) Multiple sequence alignment of the GNAT domain from mycobacterial acetyltransferases: Rv2170, PATmt (Rv0998:M. tuberculosis H37Rv), and PATms(MSMEG_5458: M. smegmatis MC2). Sequence alignment was performed using ClustalW2. Residues in the catalytic site are shown in red44. (B) Neighbor joining phylogenetic tree of Mtb Rv2170. Selected protein sequences from a blast search using the protein sequence of Rv2170 in the TB database (http://www.tbdb.org) were used as input for the phylogenetic tree. The tree was generated by using MUSCLE for alignment and PhyML for tree construction in Robust Phylogenetic Analysis interface18. The numerical values represent the branch support value.