Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 6;7:72. doi: 10.1038/s41598-017-00067-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Rv2170 modifies ICDH1 using CoA substrates from TCA cycle and methylcitrate cycle. (A) The protein acetyltransferase Rv2170 modifies ICDH1 by using CoA substrates, acetyl-CoA, succinyl-CoA, and propionyl-CoA. (B–D) ICDH1 was incubated with [1,2-¹⁴C] acetyl-CoA (B), [1-¹⁴C] propionyl-CoA (C), or [1,4-¹⁴C]succinyl-CoA (D) in the presence or absence of Rv2170. Proteins were resolved by SDS-PAGE and visualized with Coomassie Blue. Acetylation of proteins was detected by phosphor image.