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Carbon metabolism modulation by Rv2170. A diagram modeling the “preferred” metabolic fate of carbon at the metabolic node isocitrate. Rv2170, an ICDH1 acetyltransferase modulates carbon flow to either closing (A) or opening (B) toward TCA cycle during growth on stearic acid as sole carbon substrate. The direction of the dominant carbon flow is indicated by black instead of grey arrows. The CoA substrates utilized by Rv2170 are shown in blue. Symbols are as in Fig. 1A.
