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. 2017 Feb 2;7:12. doi: 10.1038/s41598-017-00047-5

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© The Author(s) 2017

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Selected pairs of representative acoustic features depicting the most distinctive speech pattern allowing differentiation between PD and controls. Individual speakers plotted in speech dimensions represented by (A) DPI in the monologue and RST in reading task, and (B) DPI in the reading task and DUS in monologue. The solid gray line represents the border of discrimination between speech negatives (subjects with unchanged speech performance) and speech positives (subjects with speech performance closer to PD speakers). The ‘.’ marks represent PD, ‘o’ for RBD and ‘x’ for controls. PD = Parkinson’s disease, RBD = rapid eye movement sleep behaviour disorder, DPI = duration of pause intervals, RST = rate of speech intervals, DUS = duration of unvoiced stops.