Table 3.
Association between myocardial steatosis and serum cardiomyocyte-enriched miRNA in patients with uncomplicated type 2 diabetes.
| β | P-value | β | P-value | ||
|---|---|---|---|---|---|
| Model 1 | Model 1 | ||||
| miR-1 | 0.360 | 0.006 | miR-133a | 0.335 | 0.008 |
| Model 2 | Model 2 | ||||
| miR-1 | 0.371 | 0.004 | miR-133a | 0.349 | 0.006 |
| Age | 0.229 | 0.069 | Age | 0.277 | 0.024 |
| Visceral fat volume | 0.139 | 0.277 | Visceral fat volume | 0.106 | 0.389 |
| Non-HDL-cholesterol | 0.233 | 0.156 | Non-HDL-cholesterol | 0.272 | 0.080 |
| Plasma triglyceride | 0.008 | 0.963 | Plasma triglyceride | −0.045 | 0.775 |
| Model 3 | Model 3 | ||||
| Association between myocardial steatosis and serum miR-1 for model 2 and each of following variables: | Association between myocardial steatosis and serum miR-133a for model 2 and each of following variables: | ||||
| i) Plasma fasting glucose | 0.387 | 0.003 | i) Plasma fasting glucose | 0.352 | 0.006 |
| ii) Plasma fasting insulin | 0.370 | 0.004 | ii) Plasma fasting insulin | 0.355 | 0.006 |
| iii) BMI | 0.384 | 0.003 | iii) BMI | 0.349 | 0.007 |
| iv) HDL-cholesterol | 0.366 | 0.005 | iv) HDL-cholesterol | 0.346 | 0.007 |
| v) Plasma NEFA | 0.411 | 0.001 | v) Plasma NEFA | 0.355 | 0.007 |
| vi) NT-proBNP | 0.378 | 0.004 | vi) NT-proBNP | 0.349 | 0.007 |
| vii) us-CRP | 0.425 | 0.001 | vii) us-CRP | 0.401 | 0.002 |
| viii) LV mass | 0.351 | 0.009 | viii) LV mass | 0.337 | 0.009 |
| ix) Ejection fraction | 0.339 | 0.008 | ix) Ejection fraction | 0.333 | 0.009 |
| x) E/Ea | 0.413 | 0.005 | x) E/Ea | 0.385 | 0.006 |
Data are expressed as standardized beta (β).