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. 2017 Mar 30;15(5):2983–2990. doi: 10.3892/mmr.2017.6416

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — ERY has a protective effect on the histological changes observed in CS-induced emphysema in rats. (A) Lung tissue sections from different groups of rats were subjected to hematoxylin and eosin staining (original magnification, ×400). (B) Quantitative analysis of alveolar airspace by MLI and MAN. *P<0.05 and **P<0.01, comparisons indicated by brackets; n=12 per group. Control rats were exposed to normal air and received daily saline injections. CS rats were exposed to CS for 12 weeks. CS + ERY rats were exposed to CS for 12 weeks and received daily injections of 100 mg/kg ERY. CS, cigarette smoke; ERY, erythromycin; MLI, mean linear intercept; MAN, mean alveolar number.