Table 1.
Specific miRNAs with key roles in myogenesis.
| miRNAs | Mechanism | Species |
|---|---|---|
| miR-29a13 | Up-regulated MyoD expression and conversely down-regulated Cdk6 expression | Mice |
| miR-1, miR-20614 | Positively regulated bovine skeletal muscle satellite cell differentiation via Pax7 and HDAC4 | Bovine |
| miR -12815 | Regulated the proliferation and differentiation of bovine skeletal muscle satellite cells by repressing Sp1 | Bovine |
| miR-145a-5p16 | Enhanced or repressed the expression of some special genes involved in the endogenous Wnt signaling pathway | Mice |
| miR-29a17 | Controlled skeletal muscle regeneration during injury and exercise downstream of FGF-2 | Mice |
| miR-20618 | Attenuated denervation-induced skeletal muscle atrophy through regulation of satellite cell differentiation via TGF- b1, Smad3, and HDAC4 signaling | Rats |
| miR-37819 | Promoted myogenic differentiation by targeting BMP4 | Mice |
| miR-20a-5p, miR-20b-5p20 | Involved in myoblast proliferation and differentiation through the auto-regulation with E2F1 | Chicken |
| miR-17-9221 | Regulated myoblast proliferation and differentiation by targeting the ENH1/Id1 signaling axis | Mice |
| miR-195, miR-49722 | Inhibited myoblast proliferation by targeting Igf1r, Insr and cyclin genes | Mice |
| miR-30-5p23 | Regulates muscle differentiation and alternative splicing of muscle-related genes by targeting MBNL | Mice |