Table I.

Correlation of the immunohistochemical staining (IHC) for SLC3A2 and clinicopathologic parameters in 50 osteosarcoma patients.

		IHC of SLC3A2
Clinicopathologic parameters	Number of cases	Positive	Negative	χ2	P-value	Odds ratio	95% CI
Age (years)
<20	31	19	12	0.363	0.547	–	–
≥20	19	10	9
Gender
Male	27	13	14	2.339	0.126	–	–
Female	23	16	7
Anatomic location
Tibia/ Femur	33	21	12	1.266	0.261	–	–
Elsewhere	17	8	9
Enneking stage
I/II	35	16	19	5.645	0.018a	7.719	1.512–39.42
III	15	13	2
Tumor size (cm3)
<50	21	8	13	5.889	0.015a	4.266	1.285–14.16
≥50	29	21	8
Degree of malignancy
Low	23	10	13	3.687	0.055	–	–
High	27	19	8
Tumor necrosis rate (%)
<90	27	17	10	0.593	0.441	–	–
≥90	23	12	11

P-value represents the probability from Pearson's Chi-square or Continuity Correction test for IHC of SLC3A2 expression between variable subgroups.

^aP<0.05, a significant difference. CI, confidence interval.