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. 2017 Mar 21;7:272. doi: 10.1038/s41598-017-00424-0

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© The Author(s) 2017

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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FLRT2 suppresses migration and adhesion. FLRT2 was downregulated with an siRNA in MCF-10A, normal breast cells (A) or upregulated in MDA-MB-231, breast cancer cells (B) and the effect on cell migration was examined. The images are taken from at least three independent experiments, and the results are shown as means with standard errors in the bar graphs. For adhesion assay, FLRT2 was upregulated or downregulated in MCF-7 (C) and MCF-10A (D), and the effect on cell adhesion was examined. The results are from three independent experiments and shown as the mean ± SD.