Table 3.
Associations of lipid biomarkers with coronary severity using logistic regression analysis.
| GS (0) | Total | Men | Women | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| GS (1–23) | GS (≥24) | P for trend | GS (1–23) | GS (≥24) | P for trend | GS (1–23) | GS (≥24) | P for trend | ||
| TG(mmol/L)* | Reference | 1.02[0.59–1.77] | 1.69 [0.96–2.98] | 0.095 | 0.87[0.42–1.77] | 1.77[0.88–3.57] | 0.084 | 1.49[0.61–3.65] | 1.31[0.46–3.68] | 0.680 |
| TC(mmol/L) | Reference | 1.03[0.91–1.16] | 1.13[1.00–1.28] | 0.045 | 0.99[0.84–1.17] | 1.17[1.00–1.38] | 0.025 | 1.12[0.94–1.33] | 1.04[0.84–1.28] | 0.573 |
| HDL-C(mmol/L) | Reference | 1.01[0.74–1.29] | 0.62[0.40–0.94] | 0.043 | 0.94[0.53–1.66] | 0.45[0.25–0.82] | 0.007 | 1.19[0.70–1.99] | 0.95[0.51–1.76] | 0.887 |
| LDL-C(mmol/L) | Reference | 1.05[0.92–1.19] | 1.24[1.08–1.42] | 0.002 | 1.05[0.88–1.25] | 1.32[1.11–1.57] | 0.001 | 1.08[0.89–1.30] | 1.11[0.89–1.39] | 0.413 |
| Non-HDL-C(mmol/L) | Reference | 1.02[0.90–1.16] | 1.20[1.05–1.36] | 0.007 | 0.98[0.83–1.17] | 1.26[1.07–1.49] | 0.002 | 1.10[0.92–1.32] | 1.05[0.84–1.31] | 0.594 |
| ApoA1(g/L) | Reference | 0.95[0.82–1.45] | 0.52[0.33–0.83] | 0.008 | 0.90[0.50–1.63] | 0.45[0.24–0.83] | 0.010 | 1.01[0.54–1.89] | 0.68[0.33–1.43] | 0.348 |
| ApoB(g/L) | Reference | 1.88[1.18–3.00] | 2.45[1.51–3.97] | <0.001 | 2.11[1.11–4.02] | 3.36[1.77–6.34] | <0.001 | 1.91[0.97–3.77] | 1.44[0.63–3.26] | 0.313 |
| Lp(a)(mg/L)* | Reference | 1.14[0.88–1.48] | 1.42[1.08–1.87] | 0.011 | 1.15[0.82–1.61] | 1.40[1.00–1.96] | 0.044 | 1.12[0.73–1.71] | 1.46[0.89–2.40] | 0.152 |
| PCSK9 (ng/ml)* | Reference | 1.63[0.58–4.58] | 5.44[1.83–16.21] | 0.002 | 2.96[0.76–11.50] | 10.79[2.74–42.45] | <0.001 | 0.81[0.16–4.13] | 1.37[0.21–9.14] | 0.817 |
| ApoC3 (μg/ml)* | Reference | 1.69[0.90–3.21] | 2.24[1.07–4.31] | 0.025 | 1.21[0.52–3.03] | 1.83[0.78–4.33] | 0.247 | 2.21[0.76–6.42] | 2.72[0.83–8.87] | 0.098 |
| sdLDL-C (mg/dl)* | Reference | 1.26[0.84–1.89] | 1.39[1.00–2.09] | 0.116 | 1.34[0.78–2.31] | 1.52[0.90–2.57] | 0.121 | 1.19[0.63–2.27] | 1.22[0.63–2.38] | 0.680 |
| largeHDL-C (mg/dl)* | Reference | 0.95[0.43–2.12] | 0.36[0.16–0.82] | 0.013 | 0.51[0.17–1.54] | 0.16[0.05–0.49] | 0.001 | 1.64[0.50–5.39] | 1.14[0.31–4.19] | 0.692 |
Multiple logistic regression analyses were performed and ORs [95% CIs] were showed with adjustment for age, gender, hypertension, HbA1c, current smoking and hs-CRP.
The bold values indicated statistical significance and were bolded to improve the readability of the table. *Log-transformed data.
Abbreviations as Table 1.