Table 4.

The interactions between lipid biomarkers on coronary severity using linear regression analysis.

Lipid parameters	Total		Men
	Coefficients	P-value	Coefficients	P-value
TC + apoB	0.046	0.056	0.078	0.013
TC + Lp(a)*	0.068	0.005	0.086	0.005
TC + PCSK9*	0.043	0.074	0.071	0.023
TC + apoC3*	0.025	0.4	0.051	0.166
HDL-C + apoA1	−0.065	0.009	−0.084	0.007
LDL-C + apoB	0.062	0.009	0.098	0.002
LDL-C + Lp(a)*	0.088	<0.001	0.109	<0.001
LDL-C + PCSK9*	0.078	<0.001	0.109	<0.001
LDL-C + apoC3*	0.06	0.036	0.093	0.009
Non-HDL-C + apoB	0.051	0.033	0.088	0.005
Non-HDL-C + Lp(a)*	0.077	<0.001	0.105	<0.001
Non-HDL-C + PCSK9*	0.056	0.02	0.095	0.003
Non-HDL-C + apoC3*	0.034	0.234	0.072	0.048
ApoA1 + largeHDL-C*	−0.066	0.025	−0.092	0.014
ApoB + Lp(a)*	0.078	<0.001	0.096	0.002
ApoB + PCSK9*	0.067	0.005	0.099	0.002
ApoB + apoC3*	0.049	0.089	0.074	0.043
ApoB + sdLDL-C*	0.029	0.368	0.054	0.201
PCSK9* + sdLDL-C*	0.031	0.334	0.048	0.249
ApoC3* + sdLDL-C*	0.016	0.621	0.035	0.409

Multiple linear regression analyses were performed and standard coefficients were showed with adjustment for age, gender, hypertension, HbA1c, current smoking and hs-CRP. The interaction terms between the lipid biomarkers in the couples were calculated as the product terms (multiplied the levels of prior lipid by the levels of posterior).

The bold values indicate statistical significance and were bolded to improve the readability of the table. *Log-transformed data.

Abbreviations as Table 1.