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Increased oxidized lipid concentrations in sciatic nerve and DRGs after ten days’ treatment with oxaliplatin. Concentrations of 9-HODE (A), 13-HODE (B), 9,10-DiHOME (C) and 12,13-DiHOME (D) using LC-MS/MS measurements from plantar paw, sciatic nerve, DRGs and dorsal horn tissue of mice treated with vehicle (black bars; 0.9% v/v DMSO) or oxaliplatin (white bars; 3 mg/kg) ten days after injection. Data represent mean ± SEM from n = 5 mice per group; *p < 0.05 unpaired student’s t-test.
