Table 2.

Descriptive characteristics and adjusted hazard ratios for predicting breast cancer mortality.

Variable	Total n = 287 n(%)/x ± s	Adjusted HR† (95% CI)	p-value
Breast cancer mortality	55 (19.2)	N/A	N/A
Age	59.0 ± 14.6	1.02 (1.00–1.04)	0.119
Personal history of breast surgery:
No	256 (89.2)	N/M*	N/M*
Benign pathology	22 (7.7)
Malignancy	7 (2.4)
Personal history of any cancer	19 (6.6)	N/M	N/M
Personal history of breast cancer	8 (2.8)	4.78 (1.82–12.57)	0.002
Premenopause	96 (33.4)	N/M	N/M
Postmenopause	189 (65.9)	N/M	N/M
Grade
Low	65 (22.6)	2.26 (1.45–3.51)*	<0.001*
Intermediate/Moderate	117 (40.8)
High	105 (36.6)
Estrogen receptor	214 (74.6)	N/M	N/M
Progesterone receptor	181 (63.1)	N/M	N/M
c-erbB2	72 (25.1)	N/M	N/M
Stage
0	13 (4.5)	1.83 (1.59–2.11)*	<0.001*
IA	93 (32.4)
IIA	73 (25.4)
IIB	45 (15.7)
IIIA	27 (9.4)
IIIC	3 (1.0)
IV	14 (4.9)
Neoadjuvant therapy	18 (6.3)	N/M	N/M
Chemotherapy	184 (64.1)	N/M	N/M
Hormone therapy	222 (77.4)	N/M	N/M
Radiotherapy	165 (57.5)	N/M	N/M
Multicentricity	50 (17.4)	1.60 (0.86–2.97)	0.140
Surgery
No	30 (10.5)	N/M	N/M
Mastectomy	239 (83.3)
Conserving	18 (6.3)
Lymphadenectomy	257 (89.5)	N/M	N/M
Diagnosis
Invasive ductal carcinoma	225 (78.4)	N/M	N/M
Invasive lobular carcinoma	38 (13.2)
Ductal/lobular in situ	12 (4.2)
Others	12 (4.2)

CI, confidence interval; HR, hazard ratio; n(%), absolute frequency (relative frequency); N/A, not applicable; N/M, not in the multivariate model; x ± s, mean ± standard deviation. *Analyzed as a quantitative variable; ^†the variables in the multivariate model are those with HR. Goodness-of-fit of the model: χ² = 165.1, p < 0.001, C-statistic = 0.85 (standard error 0.039).