Table 1.

Component loadings for the endocrine/immune variance constrained to that predictable from colony and AA severity. Networks are interpreted using loadings set in bold font.

Variables	Comp1	Comp2	Comp3
Hind paw IL-1β	0.65	0.36	0.13
Hind paw MCP-1	0.64	0.33	0.09
Hind paw TNF-α	0.57	0.31	−0.10
Hind paw KC/GRO	0.53	0.43	0.15
Hind paw IL-6	0.53	0.18	0.09
CBG	−0.49	−0.18	−0.37
Plasma TNF-α	0.46	0.41	−0.11
Hind paw IFN-ɣ	0.45	0.05	0.12
Spleen CORT	0.43	0.08	0.00
Plasma CORT	0.43	0.16	−0.14
Front paw CORT	0.41	0.27	0.13
Popliteal lymph node CORT	0.37	0.07	0.02
Hypothalamus TNF-α	−0.34	−0.02	0.11
Plasma KC/GRO	0.15	0.65	0.17
Spleen MCP-1	0.40	0.59	0.19
Plasma IL-6	0.39	0.55	0.19
Plasma IL-1β	0.03	0.44	0.22
Hypothalamus KC/GRO	0.13	0.43	0.03
Plasma MCP-1	0.38	0.42	0.18
Spleen KC/GRO	0.29	0.41	−0.15
Hypothalamus MCP-1	−0.07	0.40	−0.05
Spleen IL-6	0.31	0.40	0.13
Hippocampus KC/GRO	0.06	0.40	−0.12
Spleen IL-1β	0.31	0.39	−0.09
Spleen TNF-α	0.35	0.37	0.22
Spleen IFN-ɣ	0.03	0.36	−0.12
Plasma IFN-ɣ	0.19	0.36	0.12
Plasma ACTH	0.17	0.35	0.16
Hypothalamus IL-6	0.02	0.20	0.49
Hippocampus IL-4	0.02	−0.02	0.42
Hippocampus IL-10	0.16	−0.09	0.37
Hypothalamus IL-10	−0.26	0.04	0.36
Hind paw IL-4	0.00	0.03	0.36
Hippocampus IL-6	0.18	−0.22	0.34
Hippocampus IL-1β	0.03	0.00	0.29
Hippocampus IFN- ɣ	0.15	−0.33	0.33
Hippocampus MCP-1	−0.07	0.14	0.01
Hypothalamus IL-4	−0.21	0.05	−0.02
Hind paw CORT	0.29	0.29	0.02
Spleen IL-10	0.17	0.25	−0.05
Spleen IL-4	0.13	0.25	−0.06
Thymus CORT	0.18	−0.13	−0.07
Whole blood CORT	0.12	0.06	−0.18
Plasma IL-4	−0.02	−0.03	−0.05

Note. Values ≥ 0.34 are set in bold.

Previously reported measures²¹ are indicated in italics.