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. 2017 May 8;12:3533–3545. doi: 10.2147/IJN.S136599

Table 4.

Summary of the results of statistical analyses and model equations for the measured responses

Models Sequential P-value Lack of fit P-value SD R2 Adjusted R2 Remark
Droplet size (nm; Y1)
 Linear 0.0077 0.0278 97.25 0.7041 0.6302
 2FI 0.0238 0.0503 70.38 0.8644 0.8063
 Quadratic 0.0472* 0.1021 45.22 0.9600 0.9200 Suggested
 Cubic 0.0217 0.6675 16.29 0.9969 0.9896 Aliased
Percent dissolved in 15 min (%; Y2)
 Linear <0.0001* 0.1139 9.25 0.9287 0.9109 Suggested
 2FI 0.8107 0.0966 9.85 0.9293 0.8990
 Quadratic 0.8956 0.0618 11.4 0.9324 0.8648 Aliased
 Cubic 0.0381 0.2049 4.95 0.9923 0.9745
Total quantity (mg; Y3)
 Linear <0.0001 4.77 0.9988 0.9985
 2FI <0.0001* 0.00 1.0000 1.0000 Suggested
 Quadratic 0.00 1.0000 1.0000
 Cubic 0.00 1.0000 1.0000 Aliased

Notes:

*

The sequential P-value of <0.05 indicates that the model terms are significant up to a 95% confidence level.

The lack of fit P-value of >0.1 indicates the adequacy of the model fit. Similar values of R2 and adjusted R2 represent a good model fitting. R2, squared correlation coefficient.

Abbreviations: 2FI, two-factor interaction; SD, standard deviation.