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Characterizaton of GAR-NPs.
| Parameters | Nanoprecipitation method | After storage at 4 °C for 3 months | ||
|---|---|---|---|---|
| Drug:Polymer ratio | 1:20 | 1:10 | 1:6.66 | 1:10 |
| PLGA grade | 50:50 | 50:50 | 50:50 | 50:50 |
| Size (nm) | 90.21 ± 2.2 | 88.05 ± 2.7 | 95.45 ± 2.4 | 100 ± 4.2 |
| PDI | 0.212 ± 0.07 | 0.170 ± 0.05 | 0.237 ± 0.09 | 0.295 ± 0.08 |
| Zeta potential (mV) | −30 ± 2.2 | −28.1 ± 2.1 | −33 ± 2.4 | −27.2 ± 2.2 |
| Drug loading (DL, %) | 4.12 ± 1.9 | 9.25 ± 2.8 | 5.29 ± 2.1 | |
| Encapsulation efficiency (EE, %) | 53.43 ± 2.8 | 88.32 ± 3.3 | 60.61 ± 3.5 | |
