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. 2017 Apr 4;7:604. doi: 10.1038/s41598-017-00684-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The expression of pGSN is decreased in the CSF, but only changed slightly in the serum of MS patients. A-I, Analysis of pGSN levels in the CSF of MS patients (M1-M4) or OND patients (O1-O4) by Western blot. A-II, We calculated the relative volume percentage of each band using Quantity One software. *p < 0.05 (one-way ANOVA). B-I, Analysis of pGSN levels in the serum of MS patients (M1-M4) or OND patients (O1-O4) by Western blot. B-II, We calculated the relative volume percentage of each band using Quantity One software.