Table 2.

Clinicopathologic characteristics according to FXR and cyclin D1 protein expression in NSCLC.

Variables	NO. of patients	FXR		p-value	Cyclin D1		p-value
Variables	NO. of patients	Low (%)	High (%)	p-value	Low (%)	High (%)	p-value
Gender
Male	115	44 (38.3)	71 (61.7)	0.839^a	52 (45.2)	63 (54.8)	0.393^a
Female	45	18 (40.0)	27 (60.0)		17 (37.8)	28 (62.2)
Age (year)
≤60	61	25 (41.0)	36 (59.0)	0.649^a	25 (41.0)	36 (59.0)	0.668^a
>60	99	37 (37.4)	62 (62.6)		44 (44.4)	55 (55.6)
Stage
I-IIa	73	36 (49.3)	37 (50.7)	0.012^a	42 (57.5)	31 (42.5)	0.001^a
IIb-IV	87	26 (29.9)	61 (70.1)		27 (31.0)	60 (69.0)
Tumor size (cm)
≤3.0	51	26 (51.0)	25 (49.0)	0.03^a	29 (56.9)	22 (43.1)	0.016^a
>3.0	109	36 (33.0)	73 (67.0)		40 (36.7)	69 (63.3)
T status
T1	30	17 (56.7)	13 (43.3)	0.025^a	18 (60.0)	12 (40.0)	0.038^a
T2/T3/T4	130	45 (34.6)	85 (65.4)		51 (39.2)	79 (60.8)
N status
N0	79	36 (45.6)	43 (54.4)	0.156^a	36 (45.6)	43 (54.4)	0.537^a
N1/N2/N3	81	28 (34.6)	53 (65.4)		33 (40.7)	48 (59.3)
M status
M0	158	61 (38.6)	97 (61.4)	1^b	68 (43.0)	90 (57.0)	1^b
M1	2	1 (50.0)	1 (50.0)		1 (50.0)	1 (50.0)
NO. of positive lymph nodes
Mean		1.61	2.22	0.221^c	1.88	2.05	0.721^c
SD		2.91	3.64		3.18	3.51

^aData were analyzed using chi-square test. ^bData were analyzed using Fisher’s exact test. ^cData were analyzed using Mann-Whitney U test.