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. 2017 Apr 3;7:524. doi: 10.1038/s41598-017-00637-3

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© The Author(s) 2017

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Expression of inhibition and exhaustion receptors in CD56^bright/dim CD62L⁺CD38⁺ NK cells in HIV-1-infected individuals. (A) Gating strategy in CD56^bright/dimCD16⁺CD62L⁺CD38⁺ NK cells to determine inhibition/exhaustion receptor expression. (B and C) Ex vivo frequency of Tim-3 expression before and after TLR3 stimulation (Poly I:C) of PBMCs for 6 hours and (D) frequency of NKG2A and (E) PD-1 expression in the CD56^bright e CD56^dim NK cells of the HC (n = 5, open bar), EU (n = 5, crosshatched bar) and HIV-1-infected (n = 5, closed bar) groups. *P ≤ 0.05, **P ≤ 0.01.