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. 2017 Apr 4;7:638. doi: 10.1038/s41598-017-00630-w

Figure 4.

Figure 4

Glycerol accumulation is mediated by KIN-1 and HOSL-1. (a) The glycerol contents were elevated after 1, 3, and 7 days of cold exposure in wild type (WT) worms. The mutation in kin-1(ok338) or hosl-1(RNAi) inhibited the glycerol accumulation. These results are means ± SD of four experiments. (b) Addition of glycerol (5 mM) not only recovered the resistance to cold stress in kin-1(ok338) or hosl-1(RNAi) worms, but also enhanced the resistance to cold stress in wild type worms. P < 0.01 relative to WT.