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. 2017 Mar 31;7:523. doi: 10.1038/s41598-017-00631-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Cross-sectional classification and longitudinal time-to-HCC analysis of three different models. (A) and (B): based on miRNA-15a level only; (C) and (D): based on the logistic regression model incorporating 12 miRNAs; (E) and (F): based on the proposed HCC Risk score. Red: the cumulative incidence of the higher-risk patient stratum (N = 165); Blue: the cumulative incidence of the lower-risk patient stratum (N = 165).