Table 5.
The number of deletion, insertion, and stop codon mutations of HBV quasispecies observed.
| Genes | Mutations | Control group (72) | Experimental group (91) | P value |
|---|---|---|---|---|
| Genome | Del | 54 | 33 | — |
| Ins | 3 | 0 | — | |
| Stop codon mutations | 4 | 35 | p < 0.05 | |
| Sum | 61 | 68 | — | |
| LHBsAg | Del | 12 | 30 | p < 0.05 |
| Stopcodon mutations | 2 | 16 | p < 0.05 | |
| Sum | 14 | 46 | p < 0.05 | |
| HBxAg | Del | 23 | 2 | p < 0.05 |
| Ins | 3 | 0 | — | |
| Sum | 26 | 2 | p < 0.05 | |
| PreC/C | Del | 19 | 0 | p < 0.05 |
| Stop codon mutations | 0 | 14 | p < 0.05 | |
| Sum | 19 | 14 | — | |
| Pol | Del | 13 | 31 | — |
| Stop codon mutations | 2 | 5 | — | |
| Sum | 15 | 36 | p < 0.05 |