Table 2.

Predictors of overweight/obesity after transplant, by years after transplant and age at transplant^*

6–24 months at transplant			2–6 yr at transplant			2–20 yr at transplant
	OR (95% CI)	p**		OR (95% CI)	p		OR (95% CI)	p
1 yr after transplant (n = 3059)
Underweight at transplant	0.44 (0.28–0.71)	0.001	Underweight at transplant	0.06 (0.01–0.42)	0.005	Underweight at transplant	0.17 (0.05–0.55)	0.003
Overweight/obese at tx	2.41 (1.64–3.53)	<0.001	Overweight at transplant	2.30 (1.39–3.81)	0.001	Overweight at transplant	5.98 (4.20–8.51)	<0.001
			Obese at transplant	3.82 (2.40–6.08)	<0.001	Obese at transplant	15.7 (9.35–26.3)	<0.001
Hispanic	1.41 (0.97–2.03)	0.07	Hispanic	1.60 (0.99–0.58)	0.054	Hispanic	1.74 (1.18–2.55)	0.005
						Metabolic liver disease	0.51 (0.32–0.81)	0.005
2 yr after transplant (n = 2411)
Underweight at transplant	0.53 (0.37–0.77)	0.001				Underweight at transplant	0.29 (0.10–0.83)	0.021
Overweight/obese at tx	2.09 (1.37–3.19)	0.001	Overweight at transplant	4.08 (2.28–7.32)	<0.001	Overweight at transplant	3.38 (2.25–5.08)	<0.001
			Obese at transplant	4.82 (2.81–8.27)	<0.001	Obese at transplant	10.1 (5.62–18.0)	<0.001
Hispanic	1.34 (0.93–1.94)	0.117	Hispanic	1.54 (0.87–2.76)	0.141
Female	1.23 (0.93–1.64)	0.154	Female	0.63 (0.40–0.99)	0.043
Biliary atresia	1.81 (0.94–3.48)	0.075	Biliary atresia	2.06 (1.00–4.21)	0.049
Cholestatic liver disease	2.02 (0.94–4.37)	0.073
Other diagnoses	2.17 (0.91–5.15)	0.079
5 yr after transplant (n = 1308)
Underweight at transplant	0.44 (0.24–0.81)	0.008
Overweight/obese at tx	3.28 (1.83–5.87)	<0.001	Obese at transplant	2.19 (1.09–4.41)	0.028	Overweight at transplant	2.49 (1.29–4.82)	0.007
African American	1.78 (1.07–2.97)	0.027	Hispanic	2.25 (1.10–4.61)	0.026	Obese at transplant	5.55 (2.23–13.8)	<0.001
Other ethnicity	8.58 (1.66–44.3)	0.01	Other ethnicity	6.30 (0.90–44.2)	0.064	Other ethnicity	6.84 (1.26–37.2)	0.026
			Biliary atresia	0.35 (0.15–0.83)	0.016
			Cholestatic liver disease	0.20 (0.06–0.71)	0.016
10 yr after transplant (n = 442)
6–24 months at transplant			2–20 yr at transplant
			Overweight at transplant				2.20 (0.81–5.95)	0.122
			Female				2.30 (1.05–5.02)	0.036
Hispanic	2.29 (0.94–5.63)	0.069	Asian				5.83 (0.77–44.4)	0.089

^*All OR adjusted for age (yr) within age category, gender, race/ethnicity, primary diagnosis (indication for transplant), and weight status at transplant. OR compare groups listed to referent groups: male, Caucasian, diagnosis of acute liver failure, normal weight at transplant.

^**p-values considered significant if p < 0.05, retained in table for comparison if p < 0.15.