Table 2.
The monthly serum variation in total 25(OH)D, directly measured free 25(OH)D, calculated free 25(OH)D, bioavailable 25(OH)D, 1,25(OH)2D and DBP.
| Month of the year | Total 25(OH)D (nmol/L) | Directly measured free 25(OH)D (pmol/L) | Calculated free 25(OH)D (pmol/L) | Bio-available 25(OH)D (nmol/L) | 1,25(OH)2D (pmol/L) | DBP (mg/L) |
|---|---|---|---|---|---|---|
| January | 48.4 ± 17.4 | 9.4 ± 2.4 | 15.4 ± 7.6 | 5.8 ± 3.0 | 115.4 ± 42.1 | 248.7 ± 78.9 |
| February | 47.4 ± 20.7 | 9.1 ± 2.7 | 14.0 ± 5.2 | 5.2 ± 1.9 | 123.2 ± 43.5 | 249.1 ± 62.2 |
| March | 48.0 ± 21.0 | 8.8 ± 2.7 | 15.2 ± 6.3 | 5.1 ± 2.7 | 107.0 ± 31.2 | 243.0 ± 91.4 |
| April | 50.3 ± 20.0 | 8.5 ± 2.4 | 15.7 ± 5.6 | 5.8 ± 2.1 | 104.0 ± 35.5 | 252.0 ± 67.0 |
| May | 53.8 ± 17.1 | 9.2 ± 2.4 | 15.5 ± 4.9 | 6.0 ± 2.0 | 111.2 ± 38.6 | 263.4 ± 76.8 |
| June | 72.6 ± 26.7 | 11.8 ± 3.6 | 22.7 ± 11.1 | 8.5 ± 4.1 | 119.4 ± 39.3 | 251.0 ± 72.0 |
| July | 81.9 ± 26.2 | 15.1 ± 4.8 | 26.4 ± 12.6 | 10.0 ± 5.2 | 129.0 ± 46.3 | 253.3 ± 87.3 |
| August | 80.4 ± 29.8 | 15.7 ± 4.4 | 25.7 ± 10.3 | 9.5 ± 3.6 | 113.7 ± 39.2 | 243.1 ± 75.5 |
| September | 67.4 ± 22.7 | 14.2 ± 4.1 | 20.3 ± 9.1 | 7.4 ± 3.2 | 149.4 ± 73.4 | 260.5 ± 64.6 |
| October | 69.9 ± 24.1 | 12.3 ± 4.0 | 20.6 ± 8.4 | 8.0 ± 3.3 | 111.8 ± 35.3 | 264.9 ± 69.8 |
| November | 56.8 ± 18.3 | 10.0 ± 2.7 | 17.7 ± 8.6 | 6.7 ± 3.2 | 110.0 ± 40.8 | 254.2 ± 83.4 |
| December | 54.2 ± 22.2 | 10.3 ± 3.3 | 19.5 ± 18.1 | 7.4 ± 7.0 | 113.5 ± 40.0 | 260.7 ± 112.4 |
| All months# | ||||||
| Mean ± s.d. | 60.5 ± 25.4 | 11.1 ± 4.2 | 18.7 ± 10.0 | 7.0 ± 3.8 | 115.9 ± 42.4 | 253.9 ± 78.1 |
| 95% CI | 18.0–116.0 | 5.3–22.2 | 6.3–42.5 | 2.0–16.8 | 37.5–218.7 | 104.0–400.0 |
Values are adjusted for the fact that more subjects were included during the summer months.
1,25(OH)2D, 1,25-dihydroxy vitamin D; 25(OH)D, 25-hydroxy vitamin D; DBP, vitamin D-binding protein.
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