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. 2017 May 12;12(5):e0176280. doi: 10.1371/journal.pone.0176280

Fig 4. Effects of heat treatment of FFPE lysates on DNA quality and quantity.

Fig 4

(A) Rat liver FFPE specimens: 6 matched frozen and FFPE tissues (r1 to r3 fixed for 4 days and r4 to r6 fixed for 5 days shown in S1 Fig) were used, and the FFPE tissue lysates were treated (+) or not (-) at 95°C for 30 minutes before purification. DNA quality and quantity were determined as shown in Fig 1. (B) Human normal liver FFPE specimens: 4 matched frozen and FFPE tissues (h16, h18, h19 and h22) were used, and the FFPE tissue lysates were heat treated and examined for DNA quality (left) and quantity (right), as described in (A). **, p<0.01; *, p<0.05 by the paired t-test.