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. 2017 Apr 11;37(5):2652–2662. doi: 10.3892/or.2017.5573

Table IV.

Univariate and multivariate analysis of the prognostic parameters in early-stage cervical cancer using Cox-regression model.

Univariate analysis Multivariate analysis


P-value Hazard ratio (95% CI) P-value Hazard ratio (95% CI)
GINS2 expression <0.001 5.160 0.011 3.643
  Low (2.438–10.925) (1.347–9.850)
  High
Pelvic lymph node metastasis (PLNM) 0.008 2.716 0.127 1.827
  No (1.299–5.680) (0.843–3.962)
  Yes
SCC-Ag (ng/ml 0.099 1.854 0.862 0.922
  ≤1.5 (0.891–3.855) (0.369–2.303)
  >1.5
Recurrence <0.001 10.201 <0.001 8.523
  No (4.883–21.352) (3.944–18.416)
  Yes
Deep stromal invasion 0.543 1.304 0.669 0.823
  No (0.555–3.063) (0.337–2.008)
  Yes
Positive parametrium 0.840 1.228 0.510 2.076
  No (0.166–9.092) (0.236–18.222)
  Yes
Lymphovascular space involvement 0.735 1.282 0.971 1.032
  No (0.304–5.400) (0.190–5.623)
  Yes
Tumor size (cm) 0.523 1.371 0.481 0.675
  ≤4 (0.521–3.609) (0.227–2.013)
  >4

CI, confidential interval; GINS2, complex subunit 2; SCC-Ag, squamous cell carcinoma antigen.