Table IV.
Univariate and multivariate analysis of the prognostic parameters in early-stage cervical cancer using Cox-regression model.
Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|
P-value | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | |
GINS2 expression | <0.001 | 5.160 | 0.011 | 3.643 |
Low | (2.438–10.925) | (1.347–9.850) | ||
High | ||||
Pelvic lymph node metastasis (PLNM) | 0.008 | 2.716 | 0.127 | 1.827 |
No | (1.299–5.680) | (0.843–3.962) | ||
Yes | ||||
SCC-Ag (ng/ml | 0.099 | 1.854 | 0.862 | 0.922 |
≤1.5 | (0.891–3.855) | (0.369–2.303) | ||
>1.5 | ||||
Recurrence | <0.001 | 10.201 | <0.001 | 8.523 |
No | (4.883–21.352) | (3.944–18.416) | ||
Yes | ||||
Deep stromal invasion | 0.543 | 1.304 | 0.669 | 0.823 |
No | (0.555–3.063) | (0.337–2.008) | ||
Yes | ||||
Positive parametrium | 0.840 | 1.228 | 0.510 | 2.076 |
No | (0.166–9.092) | (0.236–18.222) | ||
Yes | ||||
Lymphovascular space involvement | 0.735 | 1.282 | 0.971 | 1.032 |
No | (0.304–5.400) | (0.190–5.623) | ||
Yes | ||||
Tumor size (cm) | 0.523 | 1.371 | 0.481 | 0.675 |
≤4 | (0.521–3.609) | (0.227–2.013) | ||
>4 |
CI, confidential interval; GINS2, complex subunit 2; SCC-Ag, squamous cell carcinoma antigen.