Skip to main content
. 2017 May 12;12(5):e0177516. doi: 10.1371/journal.pone.0177516

Fig 1. Dll1-Fc, Dll4-Fc, and Jag1-Fc alter gene expression in mouse myogenic cells.

Fig 1

(A) Scheme for analysis of Notch ligands-treated mouse muscle stem cells. (B, C) Relative mRNA expression of Notch effector genes (B) and myogenic genes (C) in mouse myogenic cells cultured with Notch ligand (Control-Fc, Dll1-Fc, Dll4-Fc, and Jag1-Fc: 5 ng/μl). Graphs represent average and 95% confidence interval from 3–4 independent experiments. Welch’s t-test was applied with Bonferroni correction. P-values are <0.05 (*) or <0.01 (**).