Table IV.
Proliferation inhibition of BxPC-3 and PANC-1 cells by natural TRAIL and MuR6-TR at different concentrations.
| Natural TRAIL
|
MuR6-TR
|
||||
|---|---|---|---|---|---|
| Concentration (µg/ml) | Inhibition rate (%)
|
Concentration (µg/ml) | Inhibition rate (%)
|
||
| BxPc-3 | PANC-1 | BxPc-3 | PANC-1 | ||
| 200 | 79.890 | 94.191 | 1 | 96.659 | 92.408 |
| 66.667 | 80.561 | 91.061 | 0.333333333 | 95.747 | 92.832 |
| 22.222 | 79.657 | 86.793 | 0.111111111 | 92.254 | 92.872 |
| 7.407 | 81.259 | 74.223 | 0.037037037 | 80.832 | 88.602 |
| 2.469 | 66.873 | 40.823 | 0.012345679 | 59.624 | 65.288 |
| 0.823 | 59.125 | 5.747 | 0.004115226 | 41.020 | 22.361 |
| 0.274 | 37.56 | 3.834 | 0.001371742 | 19.372 | 7.291 |
| 0.091 | 29.993 | 1.147 | 0.000457247 | −1.694 | −1.418 |
| 0.030 | 18.294 | −6.277 | 0.000152416 | −5.981 | 3.178 |
| 0.010 | 4.838 | −8.491 | 0.0000508052 | – | 1.037 |
TRAIL, tumor necrosis factor-related apoptosis-inducing ligand; MuR6-TR, TRAIL mutant R6.