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. 2017 May 5;39(6):1505–1515. doi: 10.3892/ijmm.2017.2975

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Imaging results of folate-receptor targeted nanoparticles (FRNPs), blank NPs and Sonovue in the 3 types of xenografts before injection and at the peak enhancement. (A, D and G) Changes in AOI after injection of FRNPs to the 3 types of xenografts under B-mode ultrasonography. (B, E and H) Corresponding changes with the injection of blank NPs. (C, F and I) Corresponding changes with injection of Sonovue. In all images, the areas circled by blue dotted lines represent the areas of interest (AOI) of tumor xenografts.