Table I.
Parameters | No. of cases | miR-30d expression
|
P-value | LRH-1 expression
|
P-value | ||
---|---|---|---|---|---|---|---|
High (37) | Low (43) | Low (29) | High (51) | ||||
Age (years) | 0.071 | 0.169 | |||||
>60 | 44 | 16 | 28 | 19 | 25 | ||
≤60 | 36 | 21 | 15 | 10 | 26 | ||
Gender | 0.262 | 0.486 | |||||
Male | 41 | 16 | 25 | 13 | 28 | ||
Female | 39 | 21 | 18 | 16 | 23 | ||
Distant metastasis | <0.05a | <0.05a | |||||
M0 | 46 | 30 | 16 | 25 | 21 | ||
M1 | 34 | 14 | 20 | 10 | 24 | ||
TNM stage | <0.01b | <0.05a | |||||
I–II | 34 | 22 | 12 | 7 | 27 | ||
III–IV | 46 | 15 | 31 | 22 | 24 | ||
Degree of differentiation | <0.05a | 0.345 | |||||
Well/moderate | 27 | 17 | 10 | 14 | 13 | ||
Poor | 53 | 20 | 33 | 21 | 32 | ||
Invasive depth | <0.05a | <0.05a | |||||
T1-T2 | 32 | 20 | 12 | 17 | 15 | ||
T3-T4 | 48 | 17 | 31 | 12 | 36 | ||
Lymph node metastasis | <0.01b | <0.05a | |||||
Yes | 36 | 25 | 11 | 18 | 18 | ||
No | 44 | 12 | 32 | 11 | 33 | ||
Tumor size (cm) | 0.262 | 0.647 | |||||
>5 | 41 | 19 | 22 | 16 | 25 | ||
≤5 | 39 | 13 | 26 | 13 | 26 |
Statistically significant difference;
highly significant difference. CRC, colorectal cancer; LRH-1, liver receptor homologue-1.