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. 2017 May 5;39(6):1421–1427. doi: 10.3892/ijmm.2017.2977

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Ghrelin inhibits the oxidized low-density lipoprotein (oxLDL)-induced inflammatory response in human umbilical vein endothelial cells (HUVECs). (A) HUVECs were either pre-treated with ghrelin or left untreated, followed by oxLDL stimulation. RT-qPCR was conducted to determine the mRNA levels of IL-6, CCL-2, ICAM-1 and VCAM-1. (B) HUVECs were pre-treated with gradiatint concentrations of ghrelin followed by oxLDL stimulation. RT-qPCR was conducted to monitor the mRNA levels of IL-6, CCL-2, ICAM-1 and VCAM-1. Quantitative experiments were repeated at least 3 times. ^*P<0.05, significant differences between different groups.