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. 2017 May 12;12(5):e0177660. doi: 10.1371/journal.pone.0177660

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© 2017 Ichikawa et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 5 — (A-B) Representative electron microscopic images of LV from Dau-treated and control hearts. Mitochondrial number and size were decreased after 9w Dau treatment when compared to mitochondria in control rabbit hearts. Scale bar = 2 μm (n = 14–17 and n = 41–53) (C) Western Blot of mitofusin-1, Opa-1, prohibitin and DRP-1 in LV from Dau-treated and control hearts. (D) Quantification of (C), n = 4–6, respectively. *p<0.05, ***p<0.001. LV, left ventricle; GAPDH, Glyceraldehyde 3-phosphate dehydrogenase; NS, not significant.