Table IV.
Characteristics of the subjects in the exome-wide association studies for ICH or subarachnoid hemorrhage.
| Characteristic | Controls | ICH | P-value | SAH | P-value |
|---|---|---|---|---|---|
| No. of subjects | 9158 | 673 | 265 | ||
| Age (years) | 58.8±13.9 | 69.4±13.9 | <0.0001 | 59.4±13.2 | 0.8515 |
| Sex (male/female, %) | 50.4/49.6 | 62.6/37.4 | <0.0001 | 41.1/58.9 | 0.0033 |
| Body mass index (kg/m2) | 23.1±3.5 | 23.1±3.8 | 0.9986 | 23.1±3.3 | 0.9672 |
| Current or former smoker (%) | 37.1 | 33.3 | 0.1836 | 31.5 | 0.1590 |
| Hypertension (%) | 42.4 | 81.4 | <0.0001 | 60.5 | <0.0001 |
| Diabetes mellitus (%) | 14.5 | 38.1 | <0.0001 | 19.6 | 0.0345 |
| Dyslipidemia (%) | 57.5 | 51.5 | 0.0152 | 41.2 | <0.0001 |
| Chronic kidney disease (%) | 18.8 | 21.2 | 0.2656 | 28.0 | 0.0052 |
| Hyperuricemia (%) | 16.0 | 15.6 | 0.8915 | 9.4 | 0.0060 |
Quantitative data are the means ± SD and were compared between subjects with ICH or SAH and controls with the Mann-Whitney U test. Categorical data were compared between 2 groups with Fisher's exact test. Based on Bonferroni's correction, a P-value of <0.0028 (0.05/18) was considered statistically significant. ICH, intracerebral hemorrhage; SAH, subarachnoid hemorrhage.